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Дата: 20.07.2024 г. - Цена: договорная Tadalafil is a chemical compound with the molecular formula C22H19N3O4. It is a medication that falls under the class of phosphodiesterase type 5 (PDE5) inhibitors. Tadalafil is commonly used for the treatment of erectile dysfunction (ED) and pulmonary arterial hypertension (PAH). Structurally, it is characterized by a pyrazino-pyrimidinone ring and a methyl piperazine moiety. Physically, tadalafil is typically a white to off-white crystalline powder.It is administered orally and is available in various dosage forms, such as tablets or capsules, for medicinal use. In terms of its pharmacological action, tadalafil works by inhibiting the enzyme PDE5, which is responsible for the degradation of cyclic guanosine monophosphate (cGMP) in the smooth muscle cells. By inhibiting PDE5, tadalafil increases the levels of cGMP, leading to relaxation of smooth muscles, vasodilation, and increased blood flow. This mechanism of action is particularly relevant to the treatment of ED, where enhanced blood flow to the penile tissue is essential for achieving and maintaining an erection.
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