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Дата: 13.07.2024 г. - Цена: договорная Product Name:Theophylline
Synonyms:Theocontin;Theodel;Theo-dur;theo-dur-sprinkle;Theofol;Theograd;Theolix;Theona P
CAS: 58-55-9
MF: C7H8N4O2
MW:180.16
EINECS:200-385-7
Theophylline Chemical Properties
Melting point 271-273 °C
Boiling point 312.97°C (rough estimate)
density 1.3640 (rough estimate)
refractive index 1.6700 (estimate)
Fp 11 °C
storage temp. 2-8°C
solubility 0.1 M HCl: soluble
form powder
pka 8.77(at 25℃)
color white
Water Solubility 8.3 g/L (20 ºC)
Merck 14,9285
BRN 13463
BCS Class 3,1
Stability: Stable. Incompatible with strong oxidizing agents.
InChIKey ZFXYFBGIUFBOJW-UHFFFAOYSA-N
LogP -0.020
CAS DataBase Reference 58-55-9(CAS DataBase Reference)
IARC 3 (Vol. 51) 1991
NIST Chemistry Reference 1,3-Dimethylxanthine(58-55-9)
EPA Substance Registry System Theophylline (58-55-9)
Description:Theophylline is a methylxanthine that acts as a weak bronchodilator. It is useful for chronic therapy and is not helpful in acute exacerbations.
Theophylline is a methylxanthine alkaloid that is a competitive inhibitor of phosphodiesterase (PDE; Ki = 100 μM). It is also a non-selective antagonist of adenosine A receptors (Ki = 14 μM for A1 and A2). Theophylline induces relaxation of feline bronchiole smooth muscle precontracted with acetylcholine (EC40 = 117 μM; EC80 = 208 μM). Formulations containing theophylline have been used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).
Chemical Properties:White to light yellow crystal powder
Uses Theophylline is tonic and skin conditioning. Its cosmetic activity is not clearly or definitively established. It is most often found in anti-cellulite products. Theophylline is in the same family of bio chemicals as caffeine. It is naturally occurring in tea.
Uses Xanthine derivative with diuretic, cardiac stimulant and smooth muscle relaxant activities; isomeric with theobromine. Small amounts occur in tea. Bronchodilator.
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